China Factory Direct Supply 99% Purity Tacrolimus FK-506 powder CAS 104987-11-3 Ouda (Health & Beauty - Other Health Ads)
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Item ID 3859565 in Category: Health & Beauty - Other Health Ads
China Factory Direct Supply 99% Purity Tacrolimus FK-506 powder CAS 104987-11-3 Ouda | |
Free Online Advertising Free Internet Web Site Advertising. UK Free Classifieds United Kingdom Free Ads Website. 100% Free Ad Posting. Canada Free Ads Popular Online Classifieds in Canada. No Sign up, No Email Required to Post. Product Details Product Name:Tacrolimus CAS No.:104987-11-3 Min. Order:1KG Purity:99 Supply Ability:50000KG/month Release date:2024/04/01 Product Name Tacrolimus Appearance solid CAS NO 104987-11-3 Molecular Formula C44H69NO12 Specification 25kg/Cardboard Drum Product Description Tacrolimus is a macrolide antibiotic. Immunosuppressants. The mechanism of action is the same as that of cyclosporine, mainly inhibiting the synthesis of interleukin-2. It is used to treat rejection of organ transplantation and is more effective in acute rejection. What is Tacrolimus? Tacrolimus, also known as fujimycin, is an immunosuppressive drug used mainly after allogeneic organ transplant to lower the risk of organ rejection. It achieves this by inhibiting the production of interleukin-2, a molecule that promotes the development and proliferation of T cells, which are vital to the body's learned (or adaptive) immune response. Tacrolimus is also used in the treatment of other T cell-mediated diseases such as eczema (for which it is applied to the skin in a medicated ointment), severe refractory uveitis after bone marrow transplants, exacerbations of minimal change disease, Kimura's disease, and the skin condition vitiligo. COA of Tacrolimus Items Specifications Results Appearance White or light yellow powder White or light yellow powder Assay 98%-102% 99.1% Water ≤ 3.0% 2.5% Related substances Ascomycin ≤ 0.8% 0.05% Dihydrotacrolimus ≤ 0.6% 0.3% Total Impurities ≤ 1.5% 0.43% Residual solvents Acetone ≤ 2000ppm ND Ethanol ≤ 2000ppm ND Heavy metals ≤ 20ppm < 20ppm Single impurity ≤ 0.6% 0.2805% Total impurity ≤ 1.5% 0.33% Conclusion Meet the specifications Usage Function of Tacrolimus Tacrolimus (FK506), a macrolide, binds to FK506 binding protein (FKBP) to form a complex and inhibits calcineurin phosphatase (calcineurin phosphatase), thereby inhibiting T lymphocyte signal transduction and IL-2 transcription, with strong Immunosuppressive properties. In recent years, as a first-line drug for liver and kidney transplantation, it has been marketed in 14 countries including Japan and the United States. Clinical experiments show that it has a good effect in transplantation of heart, lung, intestine, bone marrow, etc. At the same time, FK506 also plays an active role in the treatment of atopic dermatitis (AD), systemic lupus erythematosus (SLE), autoimmune eye disease and other autoimmune diseases. | |
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2024-11-23 (0.406 sec)